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Within these ranges, each 0.1 unit higher waist-hip-ratio was related to a links of london charms higher mortality risk in men and a 24% higher risk in women. An increased risk of mortality may be particularly related to storing fat around the waistline because fatty tissue in Links of London Cowboy Boot Charm area secretes cytokines, hormones and metabolically active compounds that can contribute to the development of chronic diseases, particularly cardiovascular diseases and cancers, suggest the authors. Links of London D Charm the main new finding of this study is that waist size increases the risk of premature death independently of body mass index (BMI), the study does support earlier findings showing that a higher body mass index is significantly related to mortality. The lowest risk of death was at a BMI of approximately 25.3 in men and Links of London Dice Charm in women. The new research forms part of the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the largest long-term prospective studies in the world. Professor Elio Riboli, the European coordinator of the EPIC study from the Department of Epidemiology and Public Health at Imperial College London, said: "Although smaller studies have suggested a link between mortality and waist size, we were surprised to see the waist size having such a powerful effect on people's health and premature death.